Qiu Ying Ying, Guan Ju Er and Fan Sheng Mei share an apartment on the 22nd floor of "Ode To Joy" apartment building. Two new neighbors have recently moved in and they don't seem like the easiest people to get along with.
In order to fight for family inheritance, Qu Xiao Xiao steals her brother's project right under his nose, but she might have bit off more than she can chew.
The ladies are worried that Ying Ying is blinded by love. Fan meets up with an old friend from college. Andie finally meet up with her internet friend Singularity.
Ying Ying is disheartened when she is terminated at her job. Guan Guan meets a potential suitor at a class reunion. Xiao Xiao successfully wins the GI project with the help of Andie.
Each of the beauties of 22nd floor have their own troubles. Andie is still concerned about her brother's welfare. Guan Guan is uncertain about how to respond to Lin's pursuit. Xiao Xiao is busy impressing her father. While Fan realize she's not as materialistic as she thinks.