Evelyn Ankers hoped to do her own singing for the film, but because of the tight production schedule producer Ben Pivar used stock recordings of Lillian Cornell for the scenes in which Ankers' character sings (and the songs are obviously older recordings since their sound quality is inferior to the rest of the soundtrack).
Isabel's song, "Our Love Will Live," uses the melody from Tchaikovsky's Piano Concerto #1.
"The Mad Ghoul" was the last film of director James P. Hogan, who finished the film in May. He died eight days before it was released on November 12,1943.
A publicity still featuring Evelyn Ankers and David Bruce showed the titles of some other recent Universal horror movies, including "Captive Wild Woman" but its title was erroneously given as "Captive Wild Women".
Part of the original Shock Theater package of 52 Universal titles released to television in 1957, followed a year later with Son of Shock, which added 20 more features.