Osmosis Jones (2001)
5/10
Good premise, but it wears thin fast
2 September 2005
This was an odd directorial choice for the Farrelly Brothers ("Dumb and Dumber," "There's Something About Mary"). It's an animated film (in parts) about the internal workings of a man's body.

The man is played by Bill Murray during the "live action" sequences. These are intercut with animated sequences that involve cells and amoebas and organs and so on and so forth voiced by the likes of William Shatner, Chris Rock, Laurence Fishburne, David Hyde Pierce (Niles from "Frasier"), Kid Rock and Ron Howard.

The cells are all animated cartoon characters who look, talk and act like humans. They live in the vast metropolis of "Frank" (Murray's character). When he feels sick, the metropolis begins to wither away.

Chris Rock voices one of Frank's defending cells who teams up with a special medical pill (swallowed by Frank) to take on Thrax (Fishburne), the maniacal germ causing Frank to feel sick.

If you think this sounds really weird, you're right. It is. But it's also very clever and unique.

The problem is that the animation is poor, the vocal talents are a bit too self-conscious and the animation is almost too realistic at time - it originally got a PG-13 rating. It's pretty seedy stuff.

The live action sequences are okay but Murray looks kind of out of it. Overall I was disappointed because I expected something funnier and cleverer, when in fact the movie dies out really quick and resorts to lame jokes like popping whiteheads on people.
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