- Though women often call up to challenge his points of view, he usually breaks down their arguments to the point where they come to agree with him.
- In the late 1990s, Leykis would occasionally merge his radio show with the equally outspoken James Whale Show from the United Kingdom, which aired in the same time slot, resulting in a single simulcast show co-hosted by Leykis and Whale via a satellite link between the two studios. In these cases, Leykis and Whale would alternate equally between American and British callers.
- Does a special segment on his radio show called "Leykis 101" where he gives men advice about women.
- Is a shock jock radio talk show host.
- Frequently warns male callers to stay away from single mothers.
- Was married to award-winning Los Angeles news reporter journalist Christina Gonzalez
- Avid hockey fan and a Los Angeles Kings season ticket holder.
- Leykis served as the co-host of "Poker Royale: Battle of the Sexes" on GSN, formerly the Game Show Network.
- Leykis was the host of "Boys Night Out," a live comedy stage show that took place at the Wiltern Theater in Los Angeles and the Paramount Theater in Seattle. The line-up of male comedians included Bobby Slayton. The shows were for men only and men were strongly discouraged from bringing girlfriends, wives or any other females.
- NewsMax.com Magazine's "Top 25 Talk Radio Host" list selected Leykis as the twenty-fifth most influential host in the nation.
- Refuses to marry again due to his failed four marriages.
- Actor Eric Bogosian studied Tom's radio style as research for his role in Talk Radio.
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