Serenity encounters a ruthlessly professional bounty hunter, Jubal Early, who will stop at nothing to retrieve River. But River, feeling unwelcome on the ship, takes a novel approach to escaping from the Alliance.
Malcolm Reynolds is a veteran and the captain of Serenity. He and his crew are smuggling goods, but they need to pick up some passengers for extra money. However, not all the passengers are what they seem.
The crew has a job in a town where Jayne once robbed the magistrate but dropped the stolen money, making him a local folk hero, and a target for the local boss.
Serenity is pulled in by an Alliance cruiser while investigating a spaceship that was attacked by Reavers. Simon and River must hide to prevent capture, while something is wrong with the lone survivor of the attacked spaceship.