- Edmund McMillen: My whole career has been me, trying to find new ways to communicate with people, because I desperately want to communicate with people, but I don't want the messy interaction of having to make friends and talk to people, because I probably don't like them.
- Jonathan Blow: If you don't see a vulnerability in somebody, you're probably not relating with them on a very personal level.
- Tommy Refenes: The things I've sacrificed are social. You kind of have to give up something to have something great.
- Edmund McMillen: [in a Skype-call with Tommy before release day] I'll send out the press release, update the website, update my blog, update my Facebook, and call it a night... What are you going to do Tommy?
- [pause]
- Tommy Refenes: Uhh... What happened? I just fell asleep.
- Edmund McMillen: Really?
- Tommy Refenes: Yeah... uh... uh... What, what did you say?
- Edmund McMillen: [laughing] Um, nothing.