In reference to a scene in the movie, Jamie Lee Curtis and Sigourney Weaver wore the same dress to the movie's premiere.
The house used by Marni's family is the same house used in Freaky Friday (2003), also starring Jamie Lee Curtis.
Kristen Bell stated in an interview aired September 24th, 2010 on The Late Late Show with Craig Ferguson (2005) that Betty White did all her own stunt work.
In the movie, Kristen Bell plays James Wolk's younger sister. In real life, Bell is five years older than Wolk.
The Sullenger Hotels group owned by Sigourney Weaver's character Ramona is named after the movie's co-producer, Betsy Sullenger.