When Grandpa's hurt back keeps him from his favorite event,Tommy enlists his friends to create the event at home. Angelica's new talking doll is a shock to her and a surprise to the babies.
Tommy's dad invents a robot dog that's allergy-free for Chuckie and Chas, but not necessarily problem-free. Angelica uses an argument between the twins to trick Phil into becoming her personal assistant.
Angelica takes advantage of a family problem to make Tommy and Chuckie play a game of house. Tommy and the babies help Chuckie take care of what he thinks is the last balloon in the whole wide world.
Tommy needs his friends' help to save Angelica after she turns into a werewolf at a scary Halloween party where their parents seem to be disappearing one by one.
Tommy and Chuckie fear their friendship is over when Angelica says they're too different to be best friends. Susie, Tommy, and Chuckie must defeat an "outer space villain" while at a sci-fi movie convention with their dads.
When the babies' favorite song gets 'stuck' in Chas's head, Tommy and the babies go on a quest to get it unstuck. Tommy and Chuckie discover that playing music might threaten their friendship.
Angelica needs the babies' help adjusting to life without her Cynthia car when her car privileges are taken away. Tommy and his friends must keep Angelica under control when she discovers a way to get any toy she asks for.
When a "professional organizer" comes over, it's up to Tommy and his friends to stop her from taking all the toys. When Tommy's parents bring home a foster puppy, Tommy must find a way to keep Spike from being replaced.
Tommy leads his friends on a daring mission to break Angelica free from her preschool. When Chuckie turns into a grown-up overnight, Tommy gets him to take the babies out on the town.