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James and Zoe work to help a teenage girl (Jessica Garza) with a rare skin blistering disorder, employing radical treatments to heal her skin in time for her to attend her school prom. Also, as Louis Keating's GSS condition gets worse, James is tempted to use his experimental cure to save him. And Malik is jealous over the special connection between James and Zoe, while Zoe awkwardly meets James' new crush, Nina (Alexis Krause).

A man is brought to the hospital by the police because they think he's drunk. But when they test his blood alcohol, it's normal so they check him out and learn his blood sugar is high so it might be a diabetic attack. But his husband shows up and says he's not diabetic. So they try to find out what's wrong with him. Eventually Wallace thinks he needs to be placed in a drug induced coma to keep him alive long enough to find a cure. And when he says he might not wake up, the husband is worried he won't be able to tell their son good bye. Malik thinks his chances are better if his placed in the coma right away but Wallace thinks they can bring him out of it long enough so that he can talk to them. It's while he's talking to them Wallace thinks he knows what happened to him and when he does he finds himself facing the possibility of trying an untested treatment again. A girl who has a skin problem goes to the hospital and while they can treat her, she only thinks of the prom which she will miss. Because she was going to go with a guy whom she likes. So Zoe tries to find a way for her to attend. And Malik is uncomfortable with how close Zoe and James are.—rcs0411@yahoo.com