Trama

A successful gene experimentation leaves Sheldon excited to procreate with Amy, and he pulls out all stops to get her on board. Meanwhile, Raj takes an interest in the cleaning lady at the university.

Despite the parts that he doesn't like about it, Amy is able to convince Sheldon to take a skin sample from him so that she can develop a brain cell from a combination of both his and hers. Sheldon is so enamored with the result of Amy's experiment that he proposes something else that shocks Amy. Sheldon does whatever he can to convince Amy to go along - those measures which would normally excite her - but she resists to the best of her ability if only because of what the end result would be. Meanwhile, Raj has met a woman, Issabella, at the university to who he is attracted, and who he would like to start dating. Beyond that physical and emotional attraction he has to her, there is one aspect of her being about which he may not be able to overcome and which colors what he says about her to his friends.—Huggo

Amy combines cells from her and Sheldon to form a brain cell. When Sheldon sees the results, he wants to take it to the next level--have a baby with Amy but she's unwilling to do it so Sheldon sets out to entice her. When Raj meets the cleaning woman at the university, he's taken with her. When the guys discover he's seeing someone he tells them he met someone at work and they assume it's another scientist and he doesn't correct them.—rcs0411@yahoo.com

Sheldon's sitting in Amy's lab lamenting how much the skin tissue sample she is about to take from him is going to hurt. Amy wants to synthesize a neural network using their joint skin cells. Sheldon is willing to do it for science though the alcohol swap is very cold. Amy gives him a count of three before he takes it. Three. Two. Swab! Sheldon doesn't even feel it, but does make her say three because of his need for closure.

Raj is in the telescope lab eating Funyuns and looking for extraterrestrial planets. Isabella (Maria Canals-Barrera) the maintenance worker comes in. Raj finds a gravitational wobble that could be an extra-solar planet that could have life on it and could be named after him. Isabella wonders if there is life, maybe it already has a name. Raj helps her with the trash and they stare at each other for a moment and then say goodbye.

While Amy is checking their brain cells, Sheldon pushes her aside and all he sees is his own eyelashes. Amy then checks and finds AstroCytes which means they have grown a primitive neural network. Sheldon then finds himself with a profound sense of creation since they used his DNA not unlike when he made sea monkeys. Since it was also using Amy's DNA, he redefines their creation as we-monkeys. They then start to test it to light and sound to see how it reacts.

The gang is around the table in Apartment 4A. Howard figures the order was screwed up since they got steamed broccoli which was for Raj. Penny is sure that he must be seeing someone since he has switched to broccoli. Finally he admits that he met a woman in the telescope room named Isabella. Leonard figures that she is an astronomer and then Raj doesn't correct him.

Bernadette is discussing the DNA experiment at Amy's place (Apartment 4B). She can't believe that one can turn skin cells into functioning brain cells. Amy counters that she turned Sheldon into a functioning boyfriend. According to Bernadette, her baby is now facing down getting ready for birth. She gets uptight when Sheldon compares their growing neural creation with her gestating human child. Sheldon agrees to think of both of them special in their own way, though they didn't have to have sex with Howard to have theirs.

Raj is helping Isabella clean the men's room calling it fun. He also mentions that he had a cleaning lady and other servants when he was growing up. Raj finds out that she is unmarried and has a 19-year-old son at UCLA studying law. She appreciates the interest, but she works two jobs and has no time for dating. She tells him "Good night", though Raj while leaving says that he still thinks that there is something going on between them.

Amy and Sheldon are very happy with their results since their little network is processing more information than most. He wants to go onto step two. Amy says that would be to try to replicate their results again. No. Sheldon wants them to have a baby. Amy asks what he is talking about? Sheldon points out that their DNA combination is truly exceptional and that it might be the next step in mankind's evolution. Amy is not ready to have a baby, even though Sheldon insists that her menstrual cycle is right for it. Sheldon then leans over and starts wiggling his bottom at her. Amy gets disgusted and leaves.

Isabella comes into the telescope room and has found that Raj has made them dinner since she was too busy to go out. He even cleaned up the next office so that she could take a break. He claimed that it was food from her homeland. Cuban food? Raj then wonders if they had Mexican food in Cuba.

Amy is discussing Sheldon's need for making a baby with Leonard and Penny. Penny wonders if he wanted to make the baby out of Lego. Then Penny asks if they would have a super-intelligent child? That was possible, but not guaranteed. Sheldon's father once picked a fight with a cactus, but that didn't include his extraterrestrial parents that sent him to earth. Reaching the top of the stairs, Amy finds a path of rose petals going into her apartment. "Oh, man!" she exclaims. Leonard and Penny have fun with whatever nightmare is behind door number two. Amy finds the lights low, candlelight, cool jazz playing and Sheldon dressed up with his hair slicked down drinking brandy from a snifter. Sheldon offers her a brandy and Amy declines. Being himself for once, Sheldon replies that it is just as well since it's disgusting. Amy tells him to stop trying to seduce her and then leaves. Sheldon tells her that he doesn't know how to open the oysters.

Raj is now having dinner with Isabella. They are talking about when they first came to America. She mentions that she has some time off on Sunday as Howard comes in. He asks if she was the astronomer that Raj met. Isabella is not happy and leaves because she is not going to waste her time with someone who is embarrassed by her. Raj runs after her to apologize and he tells her embarrassing things about him. Finally she says that he can take her out to a nice place to eat on Sunday night and it can be Pakistani food if he likes. He says he's Indian, to which Isabella says now he knows what it's like to be stereotyped.

Amy is talking to the Hofstadters. Penny wonders how much she was turned on. Amy said it felt like being hit on by Rat Pack Pee Wee Herman, meaning she wasn't. Sheldon comes in and starts to flamenco dance to Amy, the world's sexiest dance. Amy calls Sheldon ridiculous and then leaves. Leaning up against the wall outside of 4A, Amy is obviously turned on and exclaims, "That was a close one."

Title reference: Sheldon and Amy mix their DNA and incubate some brain cells.