No matter what the Preacher goes through, his clothes never get dirty
First full appearance of Herr Starr.
The first club Jesse, Tulip and Cassidy walk into is later shown to be the Kitty Cat Club but is actually Fritzel's European Jazz Pub located at 733 Bourbon Street.
The cigarette machine that Tulip uses at the laundromat advertises "Pilgrims" brand cigarettes, a probable nod to the frequent conversations the comic book Jesse Custer has with a spectral John Wayne.
When Tulip asks Jesse if he knows how many Jazz clubs there are in New Orleans Jesse responds; "187, I looked it up." 187 is the police code number used for murder/death/kill.