When Barry Allen brings Caitlyn Snow in and calls her a scientist, she claims not to be one, saying she's an ophthalmologist instead. An ophthalmologist is in fact, a scientist albeit not the kind they were looking for.
During the opening scene, the TV spot for 52 News is entitled "The Rival vs. Kid Flash", an error since the populace refers to him as "The Flash" since Barry isn't there to take the title. Only Iris, Barry, Joe, and Cisco refer to Wally as Kid Flash.
Per prior episode(s), Barry became a CSI specifically because his mom was killed, but since she's still alive in Flashpoint timeline, Barry wouldn't have necessarily become a CSI.
Barry performs many of his Flash tricks without his Flash costume/uniform but does not wear through his shoes or clothes the way he did in the beginning of Season 1.
Eddie should still be alive in the Flashpoint timeline since Barry already defeated Eobard and captured him before the events of season 1. There's no reason for Eddie to have sacrificed himself.