- A young woman struggles to survive on her own in the wake of a mysterious epidemic that has killed much of society, and forced her deep into the unforgiving wilderness.
- In the deep, rude and fearful wilderness, Ann, a solitary woman, is foraging for food relying on her limited survival skills. At the same time, in the wake of an apocalyptic global catastrophe, an appalling and virulent epidemic has already decimated most of the population, severely infecting its remaining carriers with symptoms including delirium and unpredictable behaviour coupled with aggressive outbursts. Inevitably, now that Ann's husband and baby daughter have ultimately succumbed to the invisible and inescapable plague, her days are filled with memories of a not-so-distant life defined by order and security, forcing occasionally the wary woman to hazard raids to nearby farmhouses for supplies. During one of those desperate runs, Ann will discover teenage Olivia and her wounded stepfather Chris who intend to head north, nevertheless, the quiet but ominous stillness is always blemished by the certitude that danger is everywhere, in the shape of ravenous, half-human flesh-eating predators. Under those circumstances, who shall live and who shall die?—Nick Riganas
- Sometime after a zombie-like infection decimates the world's population, Ann (Lucy Walters) struggles to survive in the woods. There are few resources and she is forced to live off the land, as abandoned houses attract dangerous, infected corpses. Throughout, Ann clings to the hope of civilization, listening to a crank radio that broadcasts an emergency message in French, a language she does not understand, and other reminders of her past life.
That past life includes her husband, Jason (Shane West), and child, an infant daughter. They are gone, and the movie explains their fate through a series of flashbacks.
On her way back from getting food from a nearby home, Ann comes across an injured man, Chris (Adam David Thompson), and his teenage stepdaughter, Olivia (Gina Piersanti). She helps them, nursing Chris back to health, but finds it difficult to trust him or Olivia.
A short time later, Chris and Olivia are about to leave when a storm rolls in; Ann allows them to stay a little while longer. Time passes and Chris and Ann form a romantic relationship, much to Olivia's irritation.
It is revealed later on that after leaving to find supplies for Ann and their daughter during the night, Jason was attacked and killed by the infected, leaving Ann to protect their child. One day, when she leaves to find food, she kills one of the infected; unknown to Ann, blood splatters onto her coat. She returns to find her daughter crying but unharmed. When Ann comforts her, the blood from her coat accidentally gets in her daughter's mouth.
Ann's daughter develops circular rashes on her belly, a telltale sign of infection. Left with no other options, Ann grinds up a bottle of aspirin, mixes it with baby formula, including droplets of her own blood, and feeds it to her daughter.
Ann decides to go North with Chris and Olivia. To do this, they must gather food from the house Ann has regularly searched so that they're able to make the journey; while Chris distracts the infected gathered in the yard, Ann and Olivia sneak into the house and start searching for food. While Ann is distracted, Olivia knocks her out, ties her up, screams, then takes the food and runs back to camp. Ann escapes, then finds Olivia and Chris under attack by the infected that Olivia drew with her scream.
Only Olivia and Ann have survived. In the car, driving down the road, Olivia rests her head on Ann's lap; Ann screams in pain and frustration over the ordeal she endured.
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