Snart's sister says she is a structural engineer, the same job that Wentworth Miller's (Snart) character, Michael, has in the TV show Prison Break (2005).
When Dr. Wells ask his computer to show him the future headlines, the bottom headline reads "Wayne Tech/Queen Inc Merger Complete," a reference to the companies owned by Bruce Wayne / Batman and Oliver Queen / Green Arrow, respectively.
Captain Cold learns Barry's identity of the Flash. In DC comics, it was Heat Wave who discovered Barry's identity and kept it to himself for his own reasons.
When talking to Dr. Wells, Barry states that everything is his fault. Wells puts his hand on Barry's shoulder and says "Brave heart, Barry." In Doctor Who (1963), during the Fifth Doctor's tenure, the Doctor would often tell his companion Tegan Jovanka, "Brave heart, Tegan" when she would be in distress.
Peyton List (Lisa Snart) has played another comic book character before, also sister to a bigger comic book character; she played Lucy Lane twice in Smallville (2001).