Amber Midthunder (Lilly Stillwater) is the real life daughter of actor David Midthunder (David Ridges) who was in prior episodes.
Guest star, Irene Bedard who plays May Stillwater, was the voice of Pocahontas in the Disney animated film. She later played Pocahontas' mother in the film Brave New World and Pocahontas was played by Q'orianka Kilcher, who made a guest appearance on Longmire Season 1 as Ayasha Roundstone.
Gregory Cruz co-starred with Baily Chase in Saving Grace.
The red letter tabs on the manila folders in the rack on the desk at the Medical Clinic on The Red spell "HERO'.
Kimberly Guerrero (Neena Wapasha) previously worked with Zahn McClarnon (Officer Mathias) on The Cherokee Word for Water.