The word 'fuck' is uttered 26 times in this episode.
This is the first episode not to feature Laurie and Patti. Matt is featured only in voice. Kevin and Nora remain the only characters to have appeared onscreen in every episode.
Nora's habit of getting shot by prostitutes is an invention of the show. In the book, she goes for lengthy bicycle rides.
The DROP conference is held in Manhattan's historic Roosevelt Hotel.
One of the protesters outside the conference has a sign that says "Tomorrow's Family Today," referencing the cult Agent Kilaney mentioned in "Gladys." A banner for Heaven's Converts (mentioned in the Pilot and "Gladys") says, "We are left in Purgatory." One conspiracy theorist has a sign claiming, "World Health Organization did it." A protester advertising PopeLive claims that the Pope is hiding in a basement in Sicily.