Misaki Saisho is the second actress to portray Kayako's ghost in the "Ju-on" films, and (at the time) the fifth actress overall.
The first "Ju-on" film written by Takashige Ichise, producer of every previous installment of both "Ju-on" and "The Grudge" film series.
Up until this film, Takashi Matsuyama had played Takeo in every single film of the franchise to feature his character.
Ayako Omura had previously played Hisayo in Katasumi (1998), a short film by Takashi Shimizu that first introduced Kayako Saeki.
The ghost of Kayako Saeki is a secondary antagonist in this remake, which focuses on Toshio's character. Kayako is brought to main in Sadako vs. Kayako (2016).