When Susan Cooper steals a moped she is wearing black stilettos. However when she tries to jump from the ramp and the moped lands in the bed of wet concrete the camera angle from the waist down shows she is wearing a pair of flat black shoes obviously indicating where the stunt performer has been substituted for Melissa McCarthy. As the camera cuts back to a medium shot of McCarthy driving through the concrete the stiletto's then reappear.
When Susan is running down the stairs towards the helicopter she is wearing black flats but when she's in the grass she's back to black high heel ankle boots.
When Aldo drops Susan (as Penny) at the bakery in Italy, she never removes her suitcase from the back seat of the sports car, but she has it with her as Aldo drives away.
Bullet fired by Agent Artingstall that hit De Luca should have also stuck Agent Cooper. An exit wound was shown on his chest. There should have also been blood splatter on Agent Cooper.
When on the plane, the amount of wine in the glass held by Susan goes up and down and back up between shots. When the camera is facing Susan, its visible that the amount of wine left in the glass is quite low. But when it faces Rayna immediately afterwards, its visible that the glass held by Susan has a full glass of wine, just as Rayna.
Hungarian license plates are invalid. During the assassination attempt on Rayna in Budapest the red car's plate is 6SE-486, the BMW's is 8GA-601 and the scooter's is 8ZE-657. They are Hungarian plates, as the 'H' country code is clearly visible. However, normal Hungarian license plates are in the form of 3 letter - 3 numbers. Custom and special plates can have other formats, but in any case they never begin with a number.
All BMW's have run flat tyres able to drive 80 km/h. This means that when Spy shoots the rear left tyre the BMW would not be affected at all.
Cooper and Ford were both able to go into the concert in Paris without tickets or passes and without security guards stopping them and Cooper was able to get on the stage to grab a microphone to warn Ford about his backpack being switched without security stopping her.
A nuclear weapon would give off a distinctive radioactive trail that can be tracked by ground-based and airborne platforms. That the CIA would not attempt to track the missing nuclear weapon using those methods, in addition to any undercover operatives, is never explained.
The Cisco IP phones in the conference room are not plugged in or active.
When Cooper and Aldo are tied up, Cooper asks Aldo to untie her hands. As she moves her body around, she puts her left hand on the floor to stabilize herself. Then she puts the arm back up behind her back as if it is tied.
When Cooper arrives at the burnt-out building in Paris, the street sign above the head of the street vendor is clearly Hungarian.
To let Bradley Fine escape in a boat, a drone blows up the jetty - but the blast wave which sends the bad guys flying back sends all the water straight upwards.
When Rayna exits the casino and several men stand up to escort her, none of the extras playing their women react but sit almost frozen like shop window dummies.
The BMW 740d in the car chase is a diesel, but the sounds coming from it are that of a petrol car. Very noticeable when it revs.
The 4- or 3-Series later on in the film is a petrol, but has been given a V8-sounding note, which it doesn't have.
When the BMW crashes into a tree, the sound explodes seconds before the crash.
After clearing out the helicopter so that Susan is the only occupant, there is a wide angle shot showing a passenger in the back.
On arrival in Paris Susan takes a taxi journey past a number of Paris landmarks. That journey would take well over an hour in quiet traffic yet the taxi meter only reads 8.60 Euros on arrival at the hotel.
When Susan arrives at Fiumicino (Rome's international airport) a LAN Airlines (from Chile) Airbus A320 is shown to be landing. Not only LAN doesn't fly to Rome, but the aircraft is incapable of making a trip from deep South America to Europe.
Italy only has 4 casinos, none of which are in Rome.
A Blue1 flight is shown landing in London and a LAN Airlines flight is shown landing in Rome. Those airlines do not service London or Rome, respectively.
When Aldo picks up Susan from Fiumicino Airport, as soon as they pull off in the car the Colosseum is seen in front of them, even though it is really over 25 km away from the airport.
When Aldo meets Susan at 'Fiumicino' he says "benvenuto", as Susan is female he should have said "benvenuta".
In Bulgaria family names of women end with "ova" not "ov". Rayna would be Raina Boyanova, not Boyanov. However, this is not a requirement, and women do have the option of using the masculine form.
Susan is given fake driving licenses which have already been signed as Carol Jenkins and Penny Morgan, which means the signatures are not in her handwriting.
Cooper should have chambered a bullet before she followed Nicola into the building in Paris. A properly trained law enforcement officer would make sure that their weapon were ready to fire when they are about to confront any threat. For a semi-automatic weapon, this means that the safety is deactivated and a round is chambered. This loads the top round from the magazine into the weapon's barrel thereby allowing this single bullet to be fired even if the magazine is removed or falls out.