The dog playing Laika died of old age between shooting days. The script was rewritten for Laika to be beaten to death by Marianne. The dead dog seen in the film is a combination of an actual cadaver and parts of a modified Samson doll (from a popular Belgian children's show)
For the voice of Luke, the directors initially tried to approach John Hurt as well as several Michael Jackson impersonators.
Each copy of the first film poster is hand-printed using the 'placenta print' technique, an arts and crafts concept for young mothers, where the placenta (still covered in the mother's blood) is used as a stamp. The result is a Rorschach test like image. For the film poster, the original baby Luke from the film is used as the stamp.
During the premiere at the Sphinx cinema in Belgium, audiences were offered popcorn in custom-made "Popcorn and vomit bags" by one of the wrestlers from the film and two girls (one of them Sofie Hoflack as her Rihanna character) in originally designed bikinis. This promotional stunt broke the theater's 25 year no-popcorn policy.
Bigorexia, from which Reggy suffers, is not a fictional concept. It is the actual (informal) term for the disorder also known as muscle dysmorphia.