Lauren from Dunstable helps Sarah sort through ten years of unused toys, clothes and out-of-date food, while germophobe Emma visits John in his cluttered Peak District home.
Specialist crime-scene cleaner Mick helps Rosemary and Julian with their cluttered home, while professional motorbike cleaner Dave meets hoarder Les and his mountain of junk.
Cafe owner Sandra helps Karl in his Norfolk boat, while Maxine visits ex-librarian Dianne, who hasn't cleaned her Norwich home in three years and eats breakfast in a cafe opposite.
Two diagnosed OCD cleaners head for Forcett Hall, North Yorkshire, where James and Alison's plans to start a B&B are being hindered by junk, unruly vines, and bird poo in the bathroom sink.
Glen from Watford and Caren from Manchester travel to the west of Ireland to help Ursula shift the mess and clutter from the upper floors of Tarbert House.