The original transformations are primarily used in this movie: Heatblast, Diamond Head, Stink Fly, Wildmutt, Four Arms, Grey Matter, and Upgrade. The ones not used are XLR8, Ghost Freak, and Ripjaws. Way Big was used, but he didn't appear until later.
Most of the original cast from Ben 10 (2005) returned to reprise their roles for this movie.
WayBig's appearance in the film resembles his design from Ben 10: Alien Force and Ben 10: Ultimate Alien.
This movie is cartoon network's first CG animated movie and also the first time the Ben 10 universe would be in full CG.