It was based on the popularity of MBC drama Daejanggeum, which aired from 2003 to 2004. Based on the time of thought of Jang Geum, the main character of the original drama "Jewel in the Palace", the whole frame is based on the original story of Jang Geum, Yeon-saeng, Geumyeong, Min Jeong-ho, and so on, adding original characters that do not appear in the drama.
The show is a spinoff from MBC's mega-hit historical drama Dae Jang Geum.
The titular character is inspired by Jang-geum (fl. early 16th century), who was reputedly the first female Royal Physician in Korean history.