This is the 99th episode of the show.
This is the first time we see Castiel drunk and we can see how he feels from the previous episode.
This is the second time that Sam and Dean have visited Blue Earth, Minnesota, the first occurring in episode 21 of season 1; Salvation (2006).
The Red Water Truck is a M715 Military Truck made by Jeep Kaiser from 1967-69. After Military Service, most were sent to Rural Fire departments and used to fight brush fires. The trucks have a 1.5 Ton load limit which makes it capable of carrying a large water tank.
The preacher's family name is Gideon. Gideons International is a large distributor of Bibles.