Brian, Stewie, Jillian & her new fiancée are eating at a restaurant with a French name that translates into "What stinks?"
Stewie tells Brian that Caitlyn Jenner is a woman. The show was prescient, because (now) Caitlyn's gender reassignment happened several years later, around season twelve.
Unlike most of the characters on the show who always wear the same clothes, guest star Lauren Conrad has several costume changes in this episode.
The title is based on the song of the same title from the 1960 Broadway musical "Bye Bye Birdie" written by Michael Stewart, lyrics by Lee Adams and music by Charles Strouse and is constantly sung by the teen-aged members of the Conrad Birdie Fan Club.