During the show the Large Hadron Collider is mentioned and the possibility it could possibly confirm the existence of the Higgs boson particle, popularly known as the "God particle". About four years later the Collider did in fact do this.
Dr Sweets mentions "that whole sell your soul at the crossroads thing." This refers to the legend that blues musician Robert Johnson met the Devil at a crossroads and sold his soul in exchange for mastery of the guitar.
Aimee Garcia, who plays Jennifer Keating, in this episode, goes onto play Ella Lopez, a Forensic officer, in Lucifer. Lucifer is a crime solving show with an odd partnership.
In keeping with the "selling your soul to the Devil at the crossroads" ~ the song that Billy Gibbons is playing on the street corner is his/ZZ Top's song "El Diablo" which, of course, means "The Devil".
Mr Nigel-Murray Ryan Cartwright and Landis Collar John Pyper-Ferguson appeared in Alphas (2011) together.