Before starring in Retina, Gary Swanson appeared in films like Vice Squad and The Bone Collector, starring Denzel Washington.
Carlos Ferrer acted as writer, director, cinematographer, composer, sound designer and visual effects artist. He personally created a fifty-minute original orchestral soundtrack, visual effects and a professionally mastered sound mix.
The crew consisted of only three people.
Lindsay Goranson did her own makeup for the movie.