The Cartman storyline is a parody of Stand and Deliver (1988). Cartman even dresses like Edward James Olmos does in the movie.
The High School Cartman teaches at in the Stand and Deliver parody storyline is the Jim Davis High, named after cartoonist and Garfield creator Jim Davis.
The photograph featuring a mouse with a human ear on its back, known as the Vacanti mouse, is authentic. It was part of a series of unconventional experiments conducted on animals. The image surfaced in 1997, triggering swift protests from both animal rights activists and religious groups. These experiments, deemed by some as 'playing God,' sparked significant controversy.