Agnese's condition rapidly deteriorates and Andrea receives the support of the whole ward to discover what's happening. The accusations against him about the falsification of data on pharmaceutical trials jeopardize his career.
Andrea Fanti, a brilliant Head of Internal Medicine, has his life turned upside down following an accident. He survives, but loses his memory of the last twelve years of his life. When he wakes up, he struggles to remember his life.
A special episode set ten years earlier. Andrea has an opportunity to make a career jump but it's hard to keep everything together: suddenly finding himself involved in a rivalry with a colleague, he risks losing sight of who he really is.
Locked in the ward in a forced quarantine, the doctors fight against time to stop a multidrug-resistant bacterium. Doc proposes a drastic and risky solution, but it is Giulia who has to decide.
Andrea is hospitalized in the Internal Medicine ward, hoping that the place most familiar to him will help him recover his memory. Giulia oversees his rehabilitation but finds herself dealing with a different man to the one she knew.
A patient sheds light on a secret about Lorenzo's private life that causes a stir throughout the ward. Gabriel and Elisa must attempt to reconstruct the life of an elderly inpatient who appears not to remember anything about himself.
A train accident turns the Internal Medicine ward into an improvised emergency room. All the doctors are required to do their best to deal with the emergency. A girl reopens an important chapter in Riccardo's past.