Just like Gorilla City from the previous episode, Atlantis is revealed to be another transplant from Earth-2.
The neurological degeneration that Cisco mentions is what affected alternate-Earth survivor Beth Kane and Alice on Batwoman (2019).
"Death of the Speed Force" is also the name of an arc from the DC Rebirth Flash comics.
Kamilla mentions Cisco getting a camera from Quimby Labs. In the comics, Ira Quimby is the villainous Mr. I.Q.
Clips of previous episodes are shown, including The Last Temptation of Barry Allen, Pt. 1 (2019), Crisis on Infinite Earths: Part Four (2020), Marathon (2020), and Grodd Friended Me (2020).