Julia Child was in the Office of Strategic Services during World War Two. This is likely where her methods of casual coercion and friendly guile depicted in the show were developed.
Bebe Neuwirth and David Hyde Pierce were both on Frasier. David as Frasier's brother and Bebe making guest appearances as Frasier's ex wife.
During the production, the cooking show Chopped did a series of competitions based on the recipes of Julia Child. In one episode Isabella Rossellini was a judge and other cast members told the contestants what would be in the baskets.
Three Star Trek connections - (1) Bebe Neuwirth appeared in ST:TNG S4:E15 "First Contact" (2) James Cromwell appeared in Star Trek First Contact as Zefram Cochrane, and (3) Robert Joy appeared as Yerid in Star Trek: Voyager S7:E16 "Work Force II."
While Bebe Neuwirth is known for the TV series Frasier, Fran Kranz appeared in Frasier S6:E1 "Good Grief" (1998)