The street address for Les Bos is 13280. This spells out "LESBO" on any calculator.
The episode has many parodies and references to the film 300 (2007).
The name of the bar is "Les Bos" (Lesbos), which is the name of a Greek island and the origin of the word "lesbian". Hence the lesbians represent the Greeks against the Persians in another 300 (2006) reference.
This is the second time a sex act is seen uncensored when Mrs Garrison is seen scissoring
The title is a reference to "dyke" a derogatory slang for a lesbian