Christopher Reeve's Legion of Doom members include Solomon Grundy, Butters (as Professor Chaos), Dougie (as General Disarray), Dr. Octopus, David Blaine, Kim Jong Il, Cheeta, Saddam Hussein, Black Manta, Dr. Victor von Doom and Osama bin Laden.
Five points is a reference to Five Points, Denver, a hotbed of gang activity and arguably the worst part of the city.
The truck that missed Jimmy and Timmy is an "EXXOFF" gas truck, a parody of Exxon.
We learn for the first time that Jimmy's father's name is Ryan and his mother is Sarah.