The title "Wire in the Blood" is a phrase that comes from T.S. Eliot's "Four Quartets": "The trilling wire in the blood / sings below inveterate scars / appeasing long-forgotten wars." It is also the name of the Book by Val McDermid that is the second in the Tony Hill/Carol Jordon series. As for the meaning, in an interview Robson Green said the phrase was taken to mean a genetic kink, something impure and unusual in the blood, that leads to the kind of psychosis Dr. Tony Hill might deal with. Series writer Val McDermid says: "Who knows what Eliot really meant by that line? Robson's explanation is as good as any. For myself, I've always taken it to be a metaphor for the thrill of adrenaline surging through the bloodstream. But we'll never know for sure".
The policeman played by Richard Frame is called Damien O'Connell. In Val McDermid's book, however, this character is called Damien Connolly.
Shadows Rising: Part 2 (2002)) from series one, "Torment" (Wire in the Blood (2002)) from series four, and "Falls the Shadow" (Falls the Shadow: Part 1 (2008) and Falls the Shadow: Part 2 (2008)) from series six. The rest are original stories created for television.