This episode is the first to provide any details whatsoever about Nog's mother, Prinadora. Indeed, it is the only episode to do so. She would be mentioned again in "Ferengi Love Songs", but no new information would be presented.
This episode is the last time a Starfleet holo-communicator is used until the U.S.S. Enterprise-E's version of it in Jornada Nas Estrelas: Nêmesis (2002). An experimental holo-communicator was also in development during the mid-23rd century, with some ships like the U.S.S. Discovery and U.S.S. Enterprise testing them in Star Trek: Discovery (2017). However the device was prone to frequent glitches, even causing a massive system's failure that disabled the Enterprise. Captain Pike ordered the device removed from the Enterprise and after that the device fell out of use in Starfleet for the next century.
The title is a parody on the expression "Dr. Livingstone, I presume," which the reporter Henry Morton Stanley used when he found the lost physician David Livingstone in the town of Ujiji on the shores of Lake Tanganyika on November 10, 1871. Coincidentally, this episode was directed by series regular director David Livingston.
This is the first appearance of Dr. Lewis Zimmerman (the creator of the Emergency Medical Hologram) as a real person on any Star Trek series, having previously appeared only as a hologram on the Voyager episodes "Projections" and "The Swarm". He appeared as a real person again in Voyager: "Life Line".
When Admiral Bennett is explaining his offer to Julian's father, he refers to Khan Singh and the Eugenics Wars, both featuring heavily in Space Seed (1967) and Jornada nas Estrelas II: A Ira de Khan (1982). This is the second time Khan is mentioned in an episode of Star Trek in which he doesn't appear. The first was A Matter Of Time (1991), in which he is mentioned by Picard.