Though actress Ruth McDevitt is credited only as "Elderly Woman", her character is actually given a name in dialogue - Miss Eggenweiller (no spelling shown) Ruth McDevitt would later join the regular cast as "Miss Emily Cowles", the columnist to whom "Miss Eggenweiller" had written in this episode.
The Ripper's house is also the Munsters' house on the Universal backlot
About 19 minutes in, when Kolchak is arguing with his editor Tony Vincenzo (Simon Oakland), there is a picture of Maj. Gregory "Pappy" Boyington behind Vincenzo. Simon Oakland went on to play Brig. Gen. Thomas Moore in Black Sheep Squadron (1976).
When Kolchak escapes the Ripper's home, there is a brief glimpse of the killer's face: brown hair with a drooping mustache and a beardless face. This corresponds exactly to the known descriptions of Jack the Ripper, according to witness statements from 1888.
Ken Lynch was set to reprise his role as Captain Warren, but the series was canceled before the episode was filmed. At the time Lynch was also co-starring in McCloud as Sergeant Grover.