When the young Christopher Wallace is writing rhymes in his notebook on the stoop, he is left-handed. Then when the grown up Christopher Wallace is in prison writing rhymes in his notebooks, he is seen writing right-handed.
When Biggie is free-styling, Lil Kim is first seen with her mole on the left side of her face. The mole changes sides on her face abruptly between shots; when it cuts back to Biggie rapping and back to her, it switches to the right side of her face. The next time we see Kim again, the mole is now back on the left side of her face.
After Biggie records "Sky is the Limit," a view of the New York skyline appears showing the New York Times building. The scene takes place in 1997, whereas construction of this building began in 2003 and was completed in 2007.
The party scenes and Notorious Big's murder are listed as occurring on March 8th, 1997, which is incorrect. The event took place after midnight on March 9, not March 8.
The coffin for the Notorious B.I.G's body is obviously too small; thus there's no way that Biggie or the actor for that matter would've fit in there.
When an older Biggie and D-Rock are running from the cops, you clearly see Biggie toss his gun away; however when he is cornered in the alley, the cops instruct him to put his piece down. Some would say there maybe two guns were used in the scene, but when the two are in the interrogation room - there is only one gun unless it was the same one he had dropped earlier.
During Christopher Wallace's first rap battle in 1989, a poster of the movie Juice, released in 1992, can quickly be seen in the background. Tupac Shakur would have still been in high school around that same time this took place.
In one scene Biggie is admiring two attractive women. One of the ladies was wearing a pair of 7 For All Mankind jeans. Those jeans didn't come out until after 2000.
Most of the movie is set around the early to late nineties, when in a majority of scenes; the random cars driving around or parked are contemporary as opposed to the ones from that decade.
A C6 Corvette Convertible is shown; a car that did not begin production until 2005. In fact, the fifth generation Chevrolet Corvette was around that time (1996), but were not released as models until 1997, the last year of his life. A fourth generation could have been used rather than a C5 or C6.
When Puffy asks Biggie when he will be going to record a new album, they are seen in an apartment with a rooftop view of New York. Judging from its position, the building they are in is the Trump World Tower, for which construction didn't begin until 1999.
Within a montage sequence of the Notorious B.I.G. becoming famous, one scene involves a group of kids jamming to B.I.G; the camera crew can be briefly seen from an apartment window on the left side of the screen.