(in credits order)
- Yolanda 'Yo-Yo' Whittaker(voice) (as Yo Yo)
- David Cross(voice)
- Shaun Ryder(voice)
- William Fichtner(voice) (as Bill Fichtner)
- Debi Mazar(voice)
- Orfeh(voice)
- Shawn Fonteno(voice) (as Solo)
- Adam Gifford(voice) (as Adam G)
- Adam Sietz(voice)
- Alice Liu(voice)
- Antonio D. Charity(voice) (as Antonio Charity)
- Asa Somers(voice) (as Asa Sommers)
- Ben Wang(voice)
- Benjamin Byron Davis(voice) (as Benjamin Davis)
- Christopher Lucas(voice) (as Chris Lucas)
- Danny Lee Clark(voice) (as Daniel Lee)
- David Shih(voice)
- Duane R. Shepard Sr.(voice) (as Duane Shepard)
- Frank Simms(voice) (as Frank Sims)
- Jamil Walker Smith(voice) (as Jamil Smith)
- Joe Holt(voice)
- Kathryn Rossetter(voice) (as Kathy Rossetter)
- Ken Foree(voice)
- Kenny Blank(voice) (as Kenn Michael)
- Lee Aaron Rosen(voice) (as Lee Rosen)
- Mamie Louise Anderson(voice) (as Mamie-Louise Anderson)
- Marcus Ho(voice)
- Matt Eyde(voice)
- Monique Lea-Gall(voice) (as Monique Lea)
- Paul McCarthy-Boyington(voice) (as Paul McCarthy Boyington)
- Sam Reich(voice)
- Eddy Toru Ohno(voice) (as Toru Ohno)
- Vernee Watson(voice) (as Vernee Watson Johnson)
Rest of cast listed alphabetically