The patriarch and matriarch of the Hubbard family, Marcus and Lavinia, are played by real-life husband and wife Fredric March and Florence Eldridge who had previously teamed onscreen in The Studio Murder Mystery (1929), Les Misérables (1935) and Mary of Scotland (1936), the last-named being Eldridge's most recent screen credit prior to ''Another Part of the Forest''. Subsequently Eldridge and March would re-team in An Act of Murder (1948) (also starring Edmond O'Brien), Christopher Columbus (1949), and - again as married Southerners - Inherit the Wind (1960), these three films comprising Eldridge's entire cinematic career subsequent to ''Another Part of the Forest''.
Dan Duryea was originally cast as Ben Hubbard: after that role was re-cast with Edmond O'Brien, Duryea (despite being eight years O'Brien's senior) was cast as younger Hubbard brother Oscar, thus playing the father of his The Little Foxes (1941) character Leo. Forty-year old Duryea's hair was bleached for the film in the belief that fair hair would make him a more believable twenty-five-year old.
"Lux Radio Theater" broadcast a 60 minute radio adaptation of the movie on
September 13, 1948 with Ann Blyth reprising her film role.
In December 1946, Universal Pictures began negotiating for the film rights for Lillian Hellman's Broadway hit ''Another Part of the Forest'', which they from the outset envisioned as a vehicle for contract player Ann Blyth, having won acclaim for her dramatic role on loan-out to Warner Bros. in Mildred Pierce (1945).
1948 Sound stage set stock units were used to construct the Hubbard Home in 1950 on Colonial Street.
The Hubbard House remained there until 1981 next to the Munster House. In 1981 the set moved to the new Colonial Street where it was placed next to the "Leave it to Beaver House"/ "Marcus Welby House" ("Any town USA" on the Universal Studio Tour). In 1988 it was to move again along with the Beaver house this time to an area of the back lot south of Falls Lake. Sometime between 2006 and 2007 it was destroyed. The Hubbard House set has appeared in many Universal Pictures and TV series, for example 'The Milkman' (1950), 'Bachelor Father' (1960)' and 'Amazing Stories' (1985).