The incredible Slaton siblings have lost an extraordinary amount of weight since appearing in 1000-Lb Sisters, and they've each achieved so many incredible weight-loss milestones over the years. The beloved unscripted series premiered in 2020. The show centers on the weight-loss journeys of 38-year-old Tammy Slaton and 37-year-old Amy Slaton, but several of their other siblings have gotten in on the action. 44-year-old Chris Combs, 43-year-old Amanda Halterman, and 48-year-old Misty Wentworth have gone on their own incredible weight loss journeys over the past few years. The series got its title from the fact that Tammy and Amy once weighed a combined 1000 pounds, but they've changed their lives completely since making their television debuts.

Most of the five Slaton siblings were overweight as children, and have struggled with weight their whole lives. They were raised by a single mother who worked a lot, so they had to feed themselves. They didn't...