Robert De Niro, Ben Stiller, Teri Polo and Blythe Danner are in early talks to star in the next installment in the “Meet the Parents” franchise. Plot details for the fourth film in the series remain under wraps.

John Hamburg is set to write the screenplay. Jane Rosenthal and Robert De Niro will produce through Tribeca Productions. Jay Roach will produce through Delirious Media. Ben Stiller and John Lesher will produce through Red Hour Films. Executive vice president of production development Matt Reilly and director of production development Jacqueline Garell will oversee the project for the studio.

“Meet the Parents” grossed over $330 million in the global box office, becoming the seventh highest-grossing film globally in 2000. Its sequels, “Meet the Fockers” and “Little Fockers,” were also box office successes, culminating in a total franchise gross of over $1.13 billion in the global box office.

Variety reviewed the first film from 2000 positively, with Todd McCarthy writing,...