Chelsea Handler has spent 25 years in the entertainment industry, meaning she's crossed paths with countless celebrities. But one actor in particular so annoyed Handler that she banned him from her talk show.

A major aspect of Handler's appeal during her run on Chelsea Lately and Netflix's Chelsea was her ability to talk to anyone. The comedian had no problem discussing any topic and could put her guests at ease.

However, actor and comedian Russell Brand pushed Handler to her limits and seemingly broke the late-night host's goodwill. Brand visited Handler three times during the seven seasons Chelsea Lately aired on E!. But Handler made sure there was never going to be a fourth time.

Handler described Brand as a "pain in the a**" in an interview with Grazia magazine (via Her). "I would never want him back," Handler said. "He stopped all of our production schedules because he needed...