In the thrilling Season 13 premiere of Ambulance, titled “Episode 1,” viewers are taken straight into the action as the weekend shift kicks off in northeast London. Airing at 9:00 Pm on Thursday, 17 October 2024, the episode begins with crewmates David and Lex preparing for their day, only to be abruptly interrupted by a chilling paramedic panic alarm blaring across the open radio channel. This alarming call signals that an ambulance crew has been attacked while attending to a patient, setting the stage for a tense and gripping episode.

As dispatch scrambles to send help to the distressed crew, David and Lex must quickly shift their focus to their first patient of the day. They arrive at the scene to assist a 59-year-old woman struggling with breathing difficulties. The episode highlights the intense and often unpredictable nature of paramedic work, showcasing the dedication and bravery of the medical professionals on the front lines.