Lina Khan, the youngest person to chair the powerful Federal Trade Commission, has come down hard on monopolies and anticompetitive behavior, so some business leaders and Wall Streeters are nudging Kamala Harris to dump her if the Democrats win the White House.

Kahn, who became FTC chief in 2021 at age 34, declined to comment on the presidential campaign, but told a New York conference, “I think it’s true that, over decades, enforcement has not always been so vigorous, and so that type of change can be uncomfortable for some people.”

LinkedIn cofounder Reid Hoffman came out publicly against Khan in a CNN interview calling her efforts a “war” on corporations. Barry Diller told CNBC, “I think she’s a dope,” but walked the comment back later.

She’s taken on heath care,

A recent story about the FTC chief in The Atlantic is titled “The Wrath At Kahn,” who has...