E! has released the trailer for Season 2 of “House of Villains,” the Joel McHale-hosted reality show that sees 10 of reality TV’s most infamous “villains” come together to outsmart and out-manipulate each other in a series of challenges to win a cash prize, and the title of “America’s Ultimate Supervillain.”

The show has been slated for a two-night premiere, with the first episode to be broadcast live on E!, Bravo, Syfy and USA on Oct. 9 at 10 p.m. Et/Pt and the second on the same time on Oct. 10. Following the premiere, the series will air in its regular Thursday timeslot at 10 p.m. Et/Pt on E! and will be available to stream on Peacock.

The trailer features the season’s malicious cast, all reunited at the iconic lair (mansion) from Season 1, with “RuPaul’s Drag Race’s” Kandy Muse iconically declaring, “You are going to come into the house of villains?...