Five arrests have been made amid a drug investigation into the death of “Friends” star Matthew Perry.

The Department of Justice said in a press conference Thursday morning that an investigation revealed a “broad underground criminal network,” including Perry’s assistant and doctors, who “took advantage” of the actor by selling him ketamine.

“This network included a live-in assistant, various go-betweens, two medical doctors and a major source of drug supply known as ‘The Ketamine Queen,'” said U.S. Attorney Martin Estrada, announcing the charges. “These defendants took advantage of Mr. Perry’s addiction issues to enrich themselves. They knew what they were doing was wrong. They knew what they were doing was risking great danger to Mr. Perry, but they did it anyways. In the end, these defendants were more interested in profiting off Mr. Perry than caring for his well being.”

The lead defendants in the case...