Lilly Wachowski is bound to direct “Trash Mountain,” a queer comedy-drama starring rising comedian and actor Caleb Hearon. The film follows a young gay man living in Chicago who returns to his hometown in Missouri following the death of his hoarder father.

Along with starring in the feature, Hearon also co-wrote the script with Ruby Caster. Colin Trevorrow, who directed Hearon in “Jurassic World Dominion,” is producing the feature with his banner Metronome Film Co., alongside Eddie Vaisman and Julia Lebedev for Sight Unseen.

“Trash Mountain” will mark the first solo directorial feature effort for Wachowski, who is best known for writing and helming the original “Matrix” trilogy with her sister, Lana Wachowski. The duo’s other projects include the lesbian crime thriller “Bound” and the colorful manga adaptation “Speed Racer.”

In recent years, Lilly has worked in television, as a co-creator of Netflix’s “Sense 8” and as a showrunner,...