Despite Jesse and Michelle's great relationship in Full House, John Stamos once had the Olsen Twins fired from the series. As the charming and fun-love Uncle Jesse, the actor spent a considerable amount of time sharing the screen with the Tanner girls. However, he has always had a special relationship with Danny Tanner's youngest child, so it's difficult to imagine that Stamos wanted Mary-Kate and Ashley booted out from the family comedy.

Appearing in Josh Peck's co-hosted podcast, The Good Guys, Stamos admits to getting the Olsen Twins fired early on in Full House.

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He cites a specific moment while filming an episode where he realized that it just wouldn't work with them playing Michelle. Read his full explanation below:

I did it. I didn’t try. Okay, we’re doing the scene. Joey and I were changing the baby,...