Over the course of more than 15 seasons, Grey’s Anatomy has seen many beloved characters die, among them Denny Duquette Jr. (Jeffrey Dean Morgan), who almost returned to the show for the third time – and here’s when and why he didn’t come back. Grey’s Anatomy has stood out for its combination of drama and comedy, though it has become best-known for its most dramatic and tragic moments, which have been a lot, especially involving some of its most popular and beloved characters.

Meredith Grey (Ellen Pompeo) and company have gone through many tragedies since season 1, and unfortunately, those include the deaths of some of the people closest to them, of which some ended up becoming fan-favorite characters. One of those is Denny Duquette, a heart patient waiting for a heart transplant who became one of Izzie Stevens’ (Katherine Heigl) most memorable love interests. Denny and Izzie actually got engaged,...