Netflix is about to introduce one of Mexico’s most legendary fictional families to the English-speaking world with “We Are the Nobles,” a new U.S. film adaptation of Mexican sensation “Nosotros los Nobles” (The Noble Family).

Eight years ago, Gaz Alazraki’s family comedy became a certified blockbuster, and still ranks as the second highest-grossing Mexican film of all time, behind “Instructions Not Included.” When Netflix was getting into original production outside of the U.S., its first effort was the series “Club of Crows,” created by Alazraki and inspired by his cinema super-hit.

Netflix is co-producing with Alazraki, who produced and directed the original, and Chris Columbus, Michael Barnathan and Mark Radcliffe from 26th Street Pictures, with whom the streamer has a larger overall deal, which also includes an untitled Chupacabra film with Jonas Cuarón, son and frequent collaborator of Alfonso Cuarón. Guido Rud, CEO and founder at FilmSharks,...