After tragedy struck Meredith and Derek and strife divided April and Jackson, Grey's Anatomy fans rallied behind Jo and Alex, who found love in their shared pain. We couldn't be happier for our curmudgeonly Alex, who hasn't had the best luck in romance. The tides have not been easy for this beloved couple, though. In season 14 alone, Alex and Jo jump over many hurdles, including Jo's estranged husband, Alex's ill mother, and Alex's heartbreaking pediatric cancer patient case. Despite the odds, Alex and Jo are finally tying the knot.

We're already arming ourselves with tissues for when they walk down the aisle. Here's a compilation of Jolex moments that made our hearts explode!